New research has identified the enzyme glutamate dehydrogenase 1 (GLUD1) as a new therapeutic target for Duchenne muscular dystrophy (DMD). In preclinical DMD mouse models, investigators demonstrated ...
An experimental study in Science Advances shows that statins, primarily fluvastatin in these experiments, may promote ...
A new study suggests that statins may activate inflammatory "danger signals" inside muscle cells, leading to weakness and ...
New research has identified the enzyme glutamate dehydrogenase 1 (GLUD1) as a new therapeutic target for Duchenne muscular dystrophy (DMD). In preclinical DMD mouse models, investigators demonstrated ...
Muscle regeneration relies on finely tuned hormonal signalling to regulate muscle stem cell activity. This Comment explores how anabolic, catabolic, metabolic and stress-related hormones influence ...
A new treatment platform developed by researchers at the University of Texas MD Anderson Cancer Center was able to deliver messenger RNA (mRNA) of the full-length DMD gene into preclinical models of ...
Findings published in The American Journal of Pathology identify GLUD1 enzyme as a potential therapeutic target for muscle restoration through metabolic reprogramming, addressing clinically unmet need ...
Thirty to fifty percent of patients with heart failure (HF) exhibit inspiratory muscle weakness (IMW). However, it is not adequately known whether IMW further impairs exercise capacity, pulmonary ...
Muscle injuries are common in the active population, and they cause the majority of player leaves in the world of sport. Depending on the severity, recovery of muscle function is quite slow and may ...
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