Creatine is best known for its role in muscle energy and exercise performance. But it also connects to the body’s methylation cycle and, potentially, common variants in the MTHFR gene. Roughly half of ...

Having two copies of the MTHFR gene mutation may raise your risk for certain health conditions, though more research is needed. You may have the mutation and not find out unless you undergo genetic ...

What Is the MTHFR Gene Mutation? The MTHFR gene mutation is a variation in the MTHFR gene. This gene normally tells your body how to make the MTHFR protein. You need this protein to process folate, ...

Life with unpredictable migraine attacks is no picnic, and the search for underlying causes and better treatment options often feels never-ending. We know there’s a strong genetic component to ...

It’s generally recommended that all women should take folic acid, both while they’re trying to get pregnant and during the first 12 weeks of pregnancy. This is because folic acid is considered to be ...

Depression. Autism. Breast cancer. Alcoholism. Type 1 diabetes. Heart disease. What do these supposedly have in common? Many alternative health websites like to talk about a supposed link between ...

Primary Sjogren’s syndrome (pSS) confers increased risk for non-Hodgkin lymphoma (NHL) development. Two common polymorphisms, the c. 677C > T and c. 1298A > C, of the methylene-tetrahydrofolate ...

David Reif, now a biologist at NC State, realized his old paper had taken on a dangerous second life when he saw it cited—not in the scientific literature, but in a court case. This interest in MTHFR ...

The central role of 5,10-methylenetetrahydrofolate reductase (MTHFR) and methylenetetrahydrofolate dehydrogenase (MTHFD1) in folate metabolism renders polymorphisms in genes encoding these enzymes ...

I remember first learning about folic acid maybe 15 years ago in school. Unless you were a chemist "folic acid" and "folate" were pretty much interchangeable words – except that folate was the form of ...

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that breaks down the amino acid homocysteine. If the MTHFR gene that codes for this enzyme mutates, it may contribute to health issues, such as ...