The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

In one sentence: DNA origami is a self-assembly technique that folds a long single-stranded DNA molecule into precisely defined nanoscale shapes using hundreds of short, computer-designed staple ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

DNA nanostructures can perform some of the complex robotic fabrication process for manufacturing and self-replication. Building things and performing work with nanorobots has been a major technical ...

A robust platform for analyzing 3D genome architecture and epigenomic features enables a deeper understanding of gene regulation in specific cell types. Researchers analyze various aspects of gene ...